Triamterene
TL;DR: Triamterene (CAS 396-01-0) is a chemical compound with molecular formula C12H11N7 and molecular weight 253.10759 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-phenylpteridine-2,4,7-triamine
Also Known As: triamterene, Dyrenium, Dytac, Pterophene, Triamteren
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H11N7 |
| Molecular Weight | 253.10759 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 130.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 253.10759 Da |
| Heavy Atoms | 19 |
| Complexity | 306.0 |
| Melting Point | 601 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | C1=CC=C(C=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N |
| InChIKey | FNYLWPVRPXGIIP-UHFFFAOYSA-N |
Product Description
Applications: Triamterene is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Triamterene (CAS 396-01-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Triamterene (CAS 396-01-0) has the molecular formula C12H11N7 and a molecular weight of 253.11 g/mol. Reported properties include a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). It is also known as triamterene and Dyrenium.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Triamterene
Property Insights of Triamterene
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Triamterene. The TPSA of 130.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Triamterene. Following Lipinski's Rule of Five, Triamterene has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Triamterene?
The CAS number of Triamterene is 396-01-0.
What is the molecular formula of Triamterene?
The molecular formula of Triamterene is C12H11N7.
What is the molecular weight of Triamterene?
The molecular weight of Triamterene is 253.10759 g/mol.
What are the applications of Triamterene?
Triamterene is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Triamterene (CAS 396-01-0) with custom...
Where can I buy Triamterene?
You can request a quote for Triamterene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Triamterene?
Yes, CoreyChem provides custom synthesis services for Triamterene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.