Trifluoroacetic anhydride
TL;DR: Trifluoroacetic anhydride (CAS 407-25-0) is a chemical compound with molecular formula C4F6O3 and molecular weight 209.97516 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate
Also Known As: TRIFLUOROACETIC ANHYDRIDE, Trifluoroacetic acid anhydride, TFAA, Perfluoroacetic anhydride, Trifluoroacetyl anhydride
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4F6O3 |
| Molecular Weight | 209.97516 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 43.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 209.97516 Da |
| Heavy Atoms | 13 |
| Complexity | 201.0 |
| Boiling Point | 39.5 °C @760 [mm Hg] |
| Density | 1.49 @25 °C |
| Vapor Pressure | 41.2 [mmHg] |
| SMILES | C(=O)(C(F)(F)F)OC(=O)C(F)(F)F |
| InChIKey | QAEDZJGFFMLHHQ-UHFFFAOYSA-N |
Product Description
Applications: Trifluoroacetic anhydride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trifluoroacetic anhydride (CAS 407-25-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Trifluoroacetic anhydride (CAS 407-25-0) is a heterocyclic building block with the molecular formula C4F6O3 and a molecular weight of 209.98 g/mol. Key physical properties include a density of 1.49 @25 °C g/cm³. It is also known as TRIFLUOROACETIC ANHYDRIDE and Trifluoroacetic acid anhydride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trifluoroacetic anhydride
Property Insights of Trifluoroacetic anhydride
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trifluoroacetic anhydride. With a topological polar surface area (TPSA) of 43.4 Ų, Trifluoroacetic anhydride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trifluoroacetic anhydride has 0 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trifluoroacetic anhydride?
The CAS number of Trifluoroacetic anhydride is 407-25-0.
What is the molecular formula of Trifluoroacetic anhydride?
The molecular formula of Trifluoroacetic anhydride is C4F6O3.
What is the molecular weight of Trifluoroacetic anhydride?
The molecular weight of Trifluoroacetic anhydride is 209.97516 g/mol.
What are the applications of Trifluoroacetic anhydride?
Trifluoroacetic anhydride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trifluoroacetic anhydride...
Where can I buy Trifluoroacetic anhydride?
You can request a quote for Trifluoroacetic anhydride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trifluoroacetic anhydride?
Yes, CoreyChem provides custom synthesis services for Trifluoroacetic anhydride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.