Clonidine
TL;DR: Clonidine (CAS 4205-90-7) is a chemical compound with molecular formula C9H9Cl2N3 and molecular weight 229.01735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
Also Known As: clonidine, Clonidin, Chlornidinum, Catapres, Duraclon
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H9Cl2N3 |
| Molecular Weight | 229.01735 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 36.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.01735 Da |
| Heavy Atoms | 14 |
| Complexity | 222.0 |
| Melting Point | 130 |
| Solubility | Insoluble in water |
| SMILES | C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl |
| InChIKey | GJSURZIOUXUGAL-UHFFFAOYSA-N |
Product Description
Applications: Clonidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Clonidine is a pharmaceutical intermediate identified by CAS number 4205-90-7 and the molecular formula C9H9Cl2N3 and a molecular weight of 229.02 g/mol. Physically, the compound has a solubility: Insoluble in water. Synonyms include clonidine and Clonidin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clonidine
Property Insights of Clonidine
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clonidine. With a topological polar surface area (TPSA) of 36.4 Ų, Clonidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clonidine has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clonidine?
The CAS number of Clonidine is 4205-90-7.
What is the molecular formula of Clonidine?
The molecular formula of Clonidine is C9H9Cl2N3.
What is the molecular weight of Clonidine?
The molecular weight of Clonidine is 229.01735 g/mol.
What are the applications of Clonidine?
Clonidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Clonidine?
You can request a quote for Clonidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clonidine?
Yes, CoreyChem provides custom synthesis services for Clonidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.