TL;DR: Midodrine Hydrochloride (CAS 43218-56-0) is a chemical compound with molecular formula C12H19ClN2O4 and molecular weight 290.10333 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide;hydrochloride
Also Known As: MIDODRINE HYDROCHLORIDE, Midodrine HCL, ProAmatine, Pro-Amatine, midodrine
Top 5 of 6 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C12H19ClN2O4 |
| Molecular Weight | 290.10333 g/mol |
| XLogP | 0.23 |
| Topological Polar Surface Area (TPSA) | 93.8 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 290.10333 Da |
| Heavy Atoms | 19 |
| Complexity | 262.0 |
| SMILES | COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl |
| InChIKey | MGCQZNBCJBRZDT-UHFFFAOYSA-N |
The XLogP value of 0.23 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Midodrine Hydrochloride. The TPSA of 93.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Midodrine Hydrochloride. Following Lipinski's Rule of Five, Midodrine Hydrochloride has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Midodrine Hydrochloride is 43218-56-0.
The molecular formula of Midodrine Hydrochloride is C12H19ClN2O4.
The molecular weight of Midodrine Hydrochloride is 290.10333 g/mol.
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