Protriptyline
TL;DR: Protriptyline (CAS 438-60-8) is a chemical compound with molecular formula C19H21N and molecular weight 263.1674 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyl)propan-1-amine
Also Known As: protriptyline, Protryptyline, Amimetilina, Triptil, Vivactil
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H21N |
| Molecular Weight | 263.1674 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 4 |
| Exact Mass | 263.1674 Da |
| Heavy Atoms | 20 |
| Complexity | 296.0 |
| Melting Point | 169-171 °C (Protriptyline HCl) |
| Solubility | 1.04 |
| SMILES | CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13 |
| InChIKey | BWPIARFWQZKAIA-UHFFFAOYSA-N |
Product Description
Applications: Protriptyline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Protriptyline (CAS 438-60-8) has the molecular formula C19H21N and a molecular weight of 263.17 g/mol. Reported properties include a solubility: 1.04. Synonyms include protriptyline and Protryptyline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Protriptyline
Property Insights of Protriptyline
The XLogP value of 4.4 indicates that Protriptyline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, Protriptyline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Protriptyline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Protriptyline?
The CAS number of Protriptyline is 438-60-8.
What is the molecular formula of Protriptyline?
The molecular formula of Protriptyline is C19H21N.
What is the molecular weight of Protriptyline?
The molecular weight of Protriptyline is 263.1674 g/mol.
What are the applications of Protriptyline?
Protriptyline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Protriptyline?
You can request a quote for Protriptyline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Protriptyline?
Yes, CoreyChem provides custom synthesis services for Protriptyline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.