5-Fluoro-2-nitrophenol
TL;DR: 5-Fluoro-2-nitrophenol (CAS 446-36-6) is a chemical compound with molecular formula C6H4FNO3 and molecular weight 157.01752 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-fluoro-2-nitrophenol
Also Known As: 5-FLUORO-2-NITROPHENOL, 3-Fluoro-6-nitrophenol, 2-Nitro-5-Fluorophenol, Phenol, 5-fluoro-2-nitro-, 5-Fluoro-2-nitro-phenol
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4FNO3 |
| Molecular Weight | 157.01752 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 66.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 157.01752 Da |
| Heavy Atoms | 11 |
| Complexity | 158.0 |
| SMILES | C1=CC(=C(C=C1F)O)[N+](=O)[O-] |
| InChIKey | QQURWFRNETXFTN-UHFFFAOYSA-N |
Product Description
Applications: 5-Fluoro-2-nitrophenol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
5-Fluoro-2-nitrophenol (CAS 446-36-6) is a heterocyclic building block with the molecular formula C6H4FNO3 and a molecular weight of 157.02 g/mol. Synonyms include 5-FLUORO-2-NITROPHENOL and 3-Fluoro-6-nitrophenol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Fluoro-2-nitrophenol
Property Insights of 5-Fluoro-2-nitrophenol
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Fluoro-2-nitrophenol. The TPSA of 66.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Fluoro-2-nitrophenol. Following Lipinski's Rule of Five, 5-Fluoro-2-nitrophenol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Fluoro-2-nitrophenol?
The CAS number of 5-Fluoro-2-nitrophenol is 446-36-6.
What is the molecular formula of 5-Fluoro-2-nitrophenol?
The molecular formula of 5-Fluoro-2-nitrophenol is C6H4FNO3.
What is the molecular weight of 5-Fluoro-2-nitrophenol?
The molecular weight of 5-Fluoro-2-nitrophenol is 157.01752 g/mol.
What are the applications of 5-Fluoro-2-nitrophenol?
5-Fluoro-2-nitrophenol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 5-Fluoro-2-nitrophenol?
You can request a quote for 5-Fluoro-2-nitrophenol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Fluoro-2-nitrophenol?
Yes, CoreyChem provides custom synthesis services for 5-Fluoro-2-nitrophenol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.