N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide
TL;DR: N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide (CAS 457-53-4) is a chemical compound with molecular formula C10H10F3NO2 and molecular weight 233.06636 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-ethoxyphenyl)-2,2,2-trifluoroacetamide
Also Known As: N-(4-ethoxyphenyl)-2,2,2-trifluoroacetamide, N-trifluoroacetyl-p-phenetidine, 2,2,2-Trifluoro-p-acetophenetidide, N-(Trifluoroacetyl)-4-ethoxyaniline, Acetamide, N-(4-ethoxyphenyl)-2,2,2-trifluoro-
Technical Specifications
| Molecular Formula | C10H10F3NO2 |
| Molecular Weight | 233.06636 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 38.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 233.06636 Da |
| Heavy Atoms | 16 |
| Complexity | 235.0 |
| SMILES | CCOC1=CC=C(C=C1)NC(=O)C(F)(F)F |
| InChIKey | SPQLXRCPBSSJCE-UHFFFAOYSA-N |
Product Description
Applications: N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide (CAS 457-53-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide (CAS 457-53-4) is a fine chemical with the molecular formula C10H10F3NO2 and a molecular weight of 233.07 g/mol. It is also known as N-(4-ethoxyphenyl)-2,2,2-trifluoroacetamide and N-trifluoroacetyl-p-phenetidine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide
Property Insights of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide
The XLogP value of 3.0 indicates that N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.3 Ų, N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
The CAS number of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is 457-53-4.
What is the molecular formula of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
The molecular formula of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is C10H10F3NO2.
What is the molecular weight of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
The molecular weight of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is 233.06636 g/mol.
What are the applications of N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide (CAS 457-53-4) with custom synthesis available from milligram to...
Where can I buy N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
You can request a quote for N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide?
Yes, CoreyChem provides custom synthesis services for N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.