Chlornaphazine
TL;DR: Chlornaphazine (CAS 494-03-1) is a chemical compound with molecular formula C14H15Cl2N and molecular weight 267.05817 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,N-bis(2-chloroethyl)naphthalen-2-amine
Also Known As: Chlornaphazine, Cloronaftina, Chloronaphthina, Chloronaphthine, Erysan
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H15Cl2N |
| Molecular Weight | 267.05817 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 267.05817 Da |
| Heavy Atoms | 17 |
| Complexity | 216.0 |
| Melting Point | 129 to 133 °F (NTP, 1992) |
| Boiling Point | 410 °F at 760 mmHg (NTP, 1992) |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
| SMILES | C1=CC=C2C=C(C=CC2=C1)N(CCCl)CCCl |
| InChIKey | XCDXSSFOJZZGQC-UHFFFAOYSA-N |
Product Description
Applications: Chlornaphazine is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Chlornaphazine (CAS 494-03-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Chlornaphazine (CAS 494-03-1) has the molecular formula C14H15Cl2N and a molecular weight of 267.06 g/mol. Reported properties include a solubility: less than 1 mg/mL at 72 °F (NTP, 1992). It is also known as Chlornaphazine and Cloronaftina.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Chlornaphazine
Property Insights of Chlornaphazine
The XLogP value of 4.5 indicates that Chlornaphazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Chlornaphazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Chlornaphazine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Chlornaphazine?
The CAS number of Chlornaphazine is 494-03-1.
What is the molecular formula of Chlornaphazine?
The molecular formula of Chlornaphazine is C14H15Cl2N.
What is the molecular weight of Chlornaphazine?
The molecular weight of Chlornaphazine is 267.05817 g/mol.
What are the applications of Chlornaphazine?
Chlornaphazine is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Chlornaphazine (CAS 494-03-1) with custom synthesis available...
Where can I buy Chlornaphazine?
You can request a quote for Chlornaphazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Chlornaphazine?
Yes, CoreyChem provides custom synthesis services for Chlornaphazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.