Melarsoprol
TL;DR: Melarsoprol (CAS 494-79-1) is a chemical compound with molecular formula C12H15AsN6OS2 and molecular weight 397.99646 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
Also Known As: MELARSOPROL, Arsobal, Mel B, Melarsoprolum, MelarsenoxidBAL
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H15AsN6OS2 |
| Molecular Weight | 397.99646 g/mol |
| XLogP | 0.32 |
| Topological Polar Surface Area (TPSA) | 174.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 397.99646 Da |
| Heavy Atoms | 22 |
| Complexity | 353.0 |
| SMILES | C1C(S[As](S1)C2=CC=C(C=C2)NC3=NC(=NC(=N3)N)N)CO |
| InChIKey | JCYZMTMYPZHVBF-UHFFFAOYSA-N |
Product Description
Applications: Melarsoprol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Melarsoprol (CAS 494-79-1) has the molecular formula C12H15AsN6OS2 and a molecular weight of 398 g/mol. Synonyms include MELARSOPROL and Arsobal.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Melarsoprol
Property Insights of Melarsoprol
The XLogP value of 0.32 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Melarsoprol. The TPSA of 174.0 Ų indicates high polarity, suggesting Melarsoprol may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Melarsoprol has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Melarsoprol?
The CAS number of Melarsoprol is 494-79-1.
What is the molecular formula of Melarsoprol?
The molecular formula of Melarsoprol is C12H15AsN6OS2.
What is the molecular weight of Melarsoprol?
The molecular weight of Melarsoprol is 397.99646 g/mol.
What are the applications of Melarsoprol?
Melarsoprol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Melarsoprol?
You can request a quote for Melarsoprol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Melarsoprol?
Yes, CoreyChem provides custom synthesis services for Melarsoprol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.