Desipramine
TL;DR: Desipramine (CAS 50-47-5) is a chemical compound with molecular formula C18H22N2 and molecular weight 266.17828 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
Also Known As: desipramine, Norimipramine, Desipramin, Desmethylimipramine, Desimipramine
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H22N2 |
| Molecular Weight | 266.17828 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 15.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 266.17828 Da |
| Heavy Atoms | 20 |
| Complexity | 267.0 |
| Melting Point | 214-218 °C |
| Boiling Point | 172-174 °C @ 0.02 MM HG |
| Solubility | 58.6 |
| SMILES | CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31 |
| InChIKey | HCYAFALTSJYZDH-UHFFFAOYSA-N |
Product Description
Applications: Desipramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Desipramine (CAS 50-47-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Desipramine (CAS 50-47-5) is a pharmaceutical intermediate with the molecular formula C18H22N2 and a molecular weight of 266.18 g/mol. Key physical properties include a solubility: 58.6. It is also known as desipramine and Norimipramine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Desipramine
Property Insights of Desipramine
The XLogP value of 4.9 indicates that Desipramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.3 Ų, Desipramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Desipramine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Desipramine?
The CAS number of Desipramine is 50-47-5.
What is the molecular formula of Desipramine?
The molecular formula of Desipramine is C18H22N2.
What is the molecular weight of Desipramine?
The molecular weight of Desipramine is 266.17828 g/mol.
What are the applications of Desipramine?
Desipramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Desipramine (CAS 50-47-5) with custom...
Where can I buy Desipramine?
You can request a quote for Desipramine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Desipramine?
Yes, CoreyChem provides custom synthesis services for Desipramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.