Niclosamide
TL;DR: Niclosamide (CAS 50-65-7) is a chemical compound with molecular formula C13H8Cl2N2O4 and molecular weight 325.9861 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Also Known As: niclosamide, Niclocide, Tredemine, Cestocid, Mansonil
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H8Cl2N2O4 |
| Molecular Weight | 325.9861 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 95.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 325.9861 Da |
| Heavy Atoms | 21 |
| Complexity | 404.0 |
| Melting Point | 230 |
| Vapor Pressure | <9.87X10-9 mm Hg at 20 °C |
| Solubility | 1.6 |
| SMILES | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
| InChIKey | RJMUSRYZPJIFPJ-UHFFFAOYSA-N |
Product Description
Applications: Niclosamide is used in pharmaceutical synthesis routes and API production, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Niclosamide (CAS 50-65-7) is a pharmaceutical intermediate with the molecular formula C13H8Cl2N2O4 and a molecular weight of 325.99 g/mol. Key physical properties include a solubility: 1.6. Synonyms include niclosamide and Niclocide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Niclosamide
Property Insights of Niclosamide
The XLogP value of 4.0 indicates that Niclosamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Niclosamide. Following Lipinski's Rule of Five, Niclosamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Niclosamide?
The CAS number of Niclosamide is 50-65-7.
What is the molecular formula of Niclosamide?
The molecular formula of Niclosamide is C13H8Cl2N2O4.
What is the molecular weight of Niclosamide?
The molecular weight of Niclosamide is 325.9861 g/mol.
What are the applications of Niclosamide?
Niclosamide is used in pharmaceutical synthesis routes and API production, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Niclosamide?
You can request a quote for Niclosamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Niclosamide?
Yes, CoreyChem provides custom synthesis services for Niclosamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.