Mk-0873

N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide

Also Known As: MK-0873|MK0873|MK 0873|GTPL9853|MK-0873 (dermatological, psoriasis)|compound 20 [PMID: 18835163]|N-Cyclopropyl-1-(3-((1-oxidopyridin-3-yl)ethynyl)phenyl)-1,4-dihydro(1,8)naphthyridin-4-one-3-carboxamide|1,8-Naphthyridine-3-carboxamide, N-cyclopropyl-1,4-dihydro-1-(3-((1-oxido-3-pyridinyl)ethynyl)phenyl)-4-oxo-|MK-0873 (dermatological, psoriasis), Merck & Co|N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide|1,8-NAPHTHYRIDINE-3-CARBOXAMIDE, N-CYCLOPROPYL-1,4-DIHYDRO-1-[3-[2-(1-OXIDO-3-PYRIDINYL)ETHYNYL]PHENYL]-4-OXO-|3-((3-(3-(cyclopropylcarbamoyl)-4-oxo-1,8-naphthyridin-1(4H)-yl)phenyl)ethynyl)pyridine 1-oxide|N-Cyclopropyl-1,4-dihydro-1-[3-[2-(1-oxido-3-pyridinyl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide|3-(2-(3-(3-(cyclopropylcarbamoyl)-4-oxo-1,4-dihydro-1,8-naphthyridin-1-yl)phenyl)ethynyl)pyridin-1-ium-1-olate|4-Oxo-1-[3-(1-oxy-pyridin-3-ylethynyl)-phenyl]-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid cyclopropylamide|N-cyclopropyl-1-(3-(2-(1-oxidopyridin-1-ium-3-yl)ethynyl)phenyl)-4-oxo-1,8-naphthyridine-3-carboxamide|N-cyclopropyl-1-[3-(1-oxido-3-pyridinylethynyl)phenyl]-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide|N-cyclopropyl-1-[3-(1-oxido-3-pyridinylethynyl)phenyl]-1,4-dihydro[1,8]naphthyridin4-one-3-carboxamide|N-cyclopropyl-1-[3-[2-(1-oxidopyridin-5-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide|N-Cyclopropyl-4-oxo-1-{3-[(1-oxo-1lambda~5~-pyridin-3-yl)ethynyl]phenyl}-1,4-dihydro-1,8-naphthyridine-3-carboxamide

Molecular Formula	C25H18N4O3
Molecular Weight	422.13788 g/mol
LogP	2.3111
Topological Polar Surface Area	90.93 Ų
Hydrogen Bond Donors	1
Hydrogen Bond Acceptors	4
Rotatable Bonds	3
Exact Mass	422.13788
Monoisotopic Mass	422.13788
Heavy Atoms	32
Complexity	1476.0354

Chemical Identifiers

CAS Number	500355-52-2
SMILES	C1CC1NC(=O)C2=CN(C3=C(C2=O)C=CC=N3)C4=CC=CC(=C4)C#CC5=C[N+](=CC=C5)[O-]