5-Bromouracil
TL;DR: 5-Bromouracil (CAS 51-20-7) is a chemical compound with molecular formula C4H3BrN2O2 and molecular weight 189.93779 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-bromo-1H-pyrimidine-2,4-dione
Also Known As: 5-Bromouracil, BROMOURACIL, Uracil, 5-bromo-, Bromuracil, 5-bromopyrimidine-2,4(1H,3H)-dione
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H3BrN2O2 |
| Molecular Weight | 189.93779 g/mol |
| XLogP | -0.2 |
| Topological Polar Surface Area (TPSA) | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 189.93779 Da |
| Heavy Atoms | 9 |
| Complexity | 199.0 |
| Melting Point | 590 °F (NTP, 1992) |
| Vapor Pressure | 0.00000023 [mmHg] |
| Solubility | less than 1 mg/mL at 75 °F (NTP, 1992) |
| SMILES | C1=C(C(=O)NC(=O)N1)Br |
| InChIKey | LQLQRFGHAALLLE-UHFFFAOYSA-N |
Product Description
Applications: 5-Bromouracil is used in biotechnology workflows and life-science research, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
5-Bromouracil (CAS 51-20-7) is a biotechnology compound with the molecular formula C4H3BrN2O2 and a molecular weight of 189.94 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 75 °F (NTP, 1992). Synonyms include 5-Bromouracil and BROMOURACIL.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Bromouracil
Property Insights of 5-Bromouracil
The XLogP value of -0.2 indicates that 5-Bromouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 58.2 Ų, 5-Bromouracil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Bromouracil has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Bromouracil?
The CAS number of 5-Bromouracil is 51-20-7.
What is the molecular formula of 5-Bromouracil?
The molecular formula of 5-Bromouracil is C4H3BrN2O2.
What is the molecular weight of 5-Bromouracil?
The molecular weight of 5-Bromouracil is 189.93779 g/mol.
What are the applications of 5-Bromouracil?
5-Bromouracil is used in biotechnology workflows and life-science research, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 5-Bromouracil?
You can request a quote for 5-Bromouracil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Bromouracil?
Yes, CoreyChem provides custom synthesis services for 5-Bromouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.