L-Hydroxyproline
TL;DR: L-Hydroxyproline (CAS 51-35-4) is a chemical compound with molecular formula C5H9NO3 and molecular weight 131.05824 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
Also Known As: L-Hydroxyproline, hydroxyproline, trans-4-Hydroxy-L-proline, L-4-hydroxyproline, 4-hydroxyproline
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H9NO3 |
| Molecular Weight | 131.05824 g/mol |
| XLogP | -3.3 |
| Topological Polar Surface Area (TPSA) | 69.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 131.05824 Da |
| Heavy Atoms | 9 |
| Complexity | 125.0 |
| Purity | ≥99% |
| Melting Point | 274°C |
| Boiling Point | Decomposes |
| Solubility | Soluble in water at 0, 25, 50, and 60 °C |
| SMILES | C1[C@H](CN[C@@H]1C(=O)O)O |
| InChIKey | PMMYEEVYMWASQN-DMTCNVIQSA-N |
Product Description
Applications: L-Hydroxyproline is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥99%. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
L-Hydroxyproline (CAS 51-35-4) is a pharmaceutical intermediate with the molecular formula C5H9NO3 and a molecular weight of 131.06 g/mol. Key physical properties include a solubility: Soluble in water at 0, 25, 50, and 60 °C. Synonyms include L-Hydroxyproline and hydroxyproline.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H54409, H54409, H54409-2.5G , H54409-10G , H54409-25G , H54409-100G , H54409-2.5G, H5534, H1637, H5877
Chemical Property Profile of L-Hydroxyproline
Property Insights of L-Hydroxyproline
The XLogP value of -3.3 indicates that L-Hydroxyproline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for L-Hydroxyproline. Following Lipinski's Rule of Five, L-Hydroxyproline has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of L-Hydroxyproline?
The CAS number of L-Hydroxyproline is 51-35-4.
What is the molecular formula of L-Hydroxyproline?
The molecular formula of L-Hydroxyproline is C5H9NO3.
What is the molecular weight of L-Hydroxyproline?
The molecular weight of L-Hydroxyproline is 131.05824 g/mol.
What are the applications of L-Hydroxyproline?
L-Hydroxyproline is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥99%. Available from CoreyChem as...
Where can I buy L-Hydroxyproline?
You can request a quote for L-Hydroxyproline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for L-Hydroxyproline?
Yes, CoreyChem provides custom synthesis services for L-Hydroxyproline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.