Mechlorethamine
TL;DR: Mechlorethamine (CAS 51-75-2) is a chemical compound with molecular formula C5H11Cl2N and molecular weight 155.02686 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-N-(2-chloroethyl)-N-methylethanamine
Also Known As: mechlorethamine, Chlormethine, Nitrogen mustard, Chlorethazine, Mustine
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H11Cl2N |
| Molecular Weight | 155.02686 g/mol |
| XLogP | 0.9 |
| Topological Polar Surface Area (TPSA) | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 4 |
| Exact Mass | 155.02686 Da |
| Heavy Atoms | 8 |
| Complexity | 43.0 |
| Melting Point | -76 °F (EPA, 1998) |
| Boiling Point | 189 °F at 18 mmHg (EPA, 1998) |
| Density | 1.118 at 77 °F (EPA, 1998) - Denser than water; will sink |
| Vapor Pressure | 0.42 [mmHg] |
| Solubility | Very soluble |
| SMILES | CN(CCCl)CCCl |
| InChIKey | HAWPXGHAZFHHAD-UHFFFAOYSA-N |
Product Description
Applications: Mechlorethamine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Mechlorethamine (CAS 51-75-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Mechlorethamine (CAS 51-75-2) is a pharmaceutical intermediate with the molecular formula C5H11Cl2N and a molecular weight of 155.03 g/mol. Key physical properties include a density of 1.118 at 77 °F (EPA, 1998) - Denser than water; will sink g/cm³, a solubility: Very soluble. It is also known as mechlorethamine and Chlormethine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Mechlorethamine
Property Insights of Mechlorethamine
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Mechlorethamine. With a topological polar surface area (TPSA) of 3.2 Ų, Mechlorethamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Mechlorethamine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Mechlorethamine?
The CAS number of Mechlorethamine is 51-75-2.
What is the molecular formula of Mechlorethamine?
The molecular formula of Mechlorethamine is C5H11Cl2N.
What is the molecular weight of Mechlorethamine?
The molecular weight of Mechlorethamine is 155.02686 g/mol.
What are the applications of Mechlorethamine?
Mechlorethamine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Mechlorethamine (CAS 51-75-2) with custom synthesis available...
Where can I buy Mechlorethamine?
You can request a quote for Mechlorethamine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Mechlorethamine?
Yes, CoreyChem provides custom synthesis services for Mechlorethamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.