Nimesulide
TL;DR: Nimesulide (CAS 51803-78-2) is a chemical compound with molecular formula C13H12N2O5S and molecular weight 308.0467 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
Also Known As: nimesulide, Aulin, Mesulid, Flogovital, Sulidene
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H12N2O5S |
| Molecular Weight | 308.0467 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 308.0467 Da |
| Heavy Atoms | 21 |
| Complexity | 450.0 |
| Melting Point | 143-144.5 °C |
| SMILES | CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 |
| InChIKey | HYWYRSMBCFDLJT-UHFFFAOYSA-N |
Product Description
Applications: Nimesulide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nimesulide is a pharmaceutical intermediate identified by CAS number 51803-78-2 and the molecular formula C13H12N2O5S and a molecular weight of 308.05 g/mol. Synonyms include nimesulide and Aulin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nimesulide
Property Insights of Nimesulide
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nimesulide. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nimesulide. Following Lipinski's Rule of Five, Nimesulide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nimesulide?
The CAS number of Nimesulide is 51803-78-2.
What is the molecular formula of Nimesulide?
The molecular formula of Nimesulide is C13H12N2O5S.
What is the molecular weight of Nimesulide?
The molecular weight of Nimesulide is 308.0467 g/mol.
What are the applications of Nimesulide?
Nimesulide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Nimesulide?
You can request a quote for Nimesulide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nimesulide?
Yes, CoreyChem provides custom synthesis services for Nimesulide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.