2-Thiophenecarboxylic acid
TL;DR: 2-Thiophenecarboxylic acid (CAS 527-72-0) is a chemical compound with molecular formula C5H4O2S and molecular weight 127.9932 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
thiophene-2-carboxylic acid
Also Known As: 2-Thiophenecarboxylic acid, THIOPHENE-2-CARBOXYLIC ACID, 2-Thenoic acid, 2-Carboxythiophene, 2-Thiophenic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H4O2S |
| Molecular Weight | 127.9932 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 65.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 127.9932 Da |
| Heavy Atoms | 8 |
| Complexity | 103.0 |
| Vapor Pressure | 0.0078 [mmHg] |
| SMILES | C1=CSC(=C1)C(=O)O |
| InChIKey | QERYCTSHXKAMIS-UHFFFAOYSA-N |
Product Description
Applications: 2-Thiophenecarboxylic acid is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Thiophenecarboxylic acid (CAS 527-72-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, 2-Thiophenecarboxylic acid (CAS 527-72-0) has the molecular formula C5H4O2S and a molecular weight of 127.99 g/mol. It is also known as 2-Thiophenecarboxylic acid and THIOPHENE-2-CARBOXYLIC ACID.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Thiophenecarboxylic acid
Property Insights of 2-Thiophenecarboxylic acid
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Thiophenecarboxylic acid. The TPSA of 65.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Thiophenecarboxylic acid. Following Lipinski's Rule of Five, 2-Thiophenecarboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Thiophenecarboxylic acid?
The CAS number of 2-Thiophenecarboxylic acid is 527-72-0.
What is the molecular formula of 2-Thiophenecarboxylic acid?
The molecular formula of 2-Thiophenecarboxylic acid is C5H4O2S.
What is the molecular weight of 2-Thiophenecarboxylic acid?
The molecular weight of 2-Thiophenecarboxylic acid is 127.9932 g/mol.
What are the applications of 2-Thiophenecarboxylic acid?
2-Thiophenecarboxylic acid is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Thiophenecarboxylic acid...
Where can I buy 2-Thiophenecarboxylic acid?
You can request a quote for 2-Thiophenecarboxylic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Thiophenecarboxylic acid?
Yes, CoreyChem provides custom synthesis services for 2-Thiophenecarboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.