Paramethasone
TL;DR: Paramethasone (CAS 53-33-8) is a chemical compound with molecular formula C22H29FO5 and molecular weight 392.1999 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Also Known As: paramethasone, Dillar, Flumethone, Paramezone, Cassenne
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H29FO5 |
| Molecular Weight | 392.1999 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1999 Da |
| Heavy Atoms | 28 |
| Complexity | 790.0 |
| Solubility | Fluffy, practically white, crystalline powder. Sol in chloroform, ether, and methanol; odorless /acetate/ |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)C)F |
| InChIKey | MKPDWECBUAZOHP-AFYJWTTESA-N |
Product Description
Applications: Paramethasone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Paramethasone is a pharmaceutical intermediate identified by CAS number 53-33-8 and the molecular formula C22H29FO5 and a molecular weight of 392.2 g/mol. Physically, the compound has a solubility: Fluffy, practically white, crystalline powder. Sol in chloroform, ether, and methanol; odorless /acetate/. Synonyms include paramethasone and Dillar.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Paramethasone
Property Insights of Paramethasone
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Paramethasone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Paramethasone. Following Lipinski's Rule of Five, Paramethasone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Paramethasone?
The CAS number of Paramethasone is 53-33-8.
What is the molecular formula of Paramethasone?
The molecular formula of Paramethasone is C22H29FO5.
What is the molecular weight of Paramethasone?
The molecular weight of Paramethasone is 392.1999 g/mol.
What are the applications of Paramethasone?
Paramethasone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Paramethasone?
You can request a quote for Paramethasone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Paramethasone?
Yes, CoreyChem provides custom synthesis services for Paramethasone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.