Flufenamic Acid
TL;DR: Flufenamic Acid (CAS 530-78-9) is a chemical compound with molecular formula C14H10F3NO2 and molecular weight 281.06638 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
氟芬那酸
2-[3-(trifluoromethyl)anilino]benzoic acid
Also Known As: flufenamic acid, Arlef, Achless, Fluphenamic acid, Nichisedan
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H10F3NO2 |
| Molecular Weight | 281.06638 g/mol |
| XLogP | 5.2 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 281.06638 Da |
| Heavy Atoms | 20 |
| Complexity | 346.0 |
| Melting Point | 133.5 |
| Solubility | 9.09 |
| SMILES | C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F |
| InChIKey | LPEPZBJOKDYZAD-UHFFFAOYSA-N |
Product Description
Applications: Flufenamic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Flufenamic Acid (CAS 530-78-9) has the molecular formula C14H10F3NO2 and a molecular weight of 281.07 g/mol. Reported properties include a solubility: 9.09. Synonyms include flufenamic acid and Arlef.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Flufenamic Acid
Property Insights of Flufenamic Acid
The XLogP value of 5.2 indicates that Flufenamic Acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.3 Ų, Flufenamic Acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Flufenamic Acid has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Flufenamic Acid?
The CAS number of Flufenamic Acid is 530-78-9.
What is the molecular formula of Flufenamic Acid?
The molecular formula of Flufenamic Acid is C14H10F3NO2.
What is the molecular weight of Flufenamic Acid?
The molecular weight of Flufenamic Acid is 281.06638 g/mol.
What are the applications of Flufenamic Acid?
Flufenamic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Flufenamic Acid?
You can request a quote for Flufenamic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Flufenamic Acid?
Yes, CoreyChem provides custom synthesis services for Flufenamic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.