Mefloquine
TL;DR: Mefloquine (CAS 53230-10-7) is a chemical compound with molecular formula C17H16F6N2O and molecular weight 378.11667 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol
Also Known As: mefloquine, Lariam, Mefloquina, Mefloquinone, Mefloquinum
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H16F6N2O |
| Molecular Weight | 378.11667 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 45.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.11667 Da |
| Heavy Atoms | 26 |
| Complexity | 483.0 |
| Melting Point | 250-254 |
| Boiling Point | 415.7±40.0 °C |
| Density | Crystal density: 1.432 g/cu cm |
| Solubility | 1.806 |
| SMILES | C1CCNC(C1)C(C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O |
| InChIKey | XEEQGYMUWCZPDN-UHFFFAOYSA-N |
Product Description
Applications: Mefloquine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Mefloquine (CAS 53230-10-7) is a pharmaceutical intermediate with the molecular formula C17H16F6N2O and a molecular weight of 378.12 g/mol. Key physical properties include a density of Crystal density: 1.432 g/cu cm g/cm³, a solubility: 1.806. Synonyms include mefloquine and Lariam.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Mefloquine
Property Insights of Mefloquine
The XLogP value of 3.6 indicates that Mefloquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, Mefloquine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Mefloquine has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Mefloquine?
The CAS number of Mefloquine is 53230-10-7.
What is the molecular formula of Mefloquine?
The molecular formula of Mefloquine is C17H16F6N2O.
What is the molecular weight of Mefloquine?
The molecular weight of Mefloquine is 378.11667 g/mol.
What are the applications of Mefloquine?
Mefloquine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Mefloquine?
You can request a quote for Mefloquine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Mefloquine?
Yes, CoreyChem provides custom synthesis services for Mefloquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.