Nefopam Hydrochloride
TL;DR: Nefopam Hydrochloride (CAS 53648-31-0) is a chemical compound with molecular formula C17H20ClNO and molecular weight 289.12335 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride
Also Known As: Nefopam hydrochloride, Nefopam HCl, Acupan, nefopam, Pallopikeron
Application Areas
Top 5 of 6 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H20ClNO |
| Molecular Weight | 289.12335 g/mol |
| XLogP | 3.6598 |
| Topological Polar Surface Area (TPSA) | 13.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 289.12335 Da |
| Heavy Atoms | 20 |
| Complexity | 274.0 |
| Solubility | >43.5 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl |
| InChIKey | CNNVSINJDJNHQK-UHFFFAOYSA-N |
Product Description
Applications: Nefopam Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nefopam Hydrochloride (CAS 53648-31-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Nefopam Hydrochloride (CAS 53648-31-0) has the molecular formula C17H20ClNO and a molecular weight of 289.12 g/mol. Reported properties include a solubility: >43.5 [ug/mL] (The mean of the results at pH 7.4). It is also known as Nefopam hydrochloride and Nefopam HCl.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nefopam Hydrochloride
Property Insights of Nefopam Hydrochloride
The XLogP value of 3.6598 indicates that Nefopam Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 13.7 Ų, Nefopam Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nefopam Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nefopam Hydrochloride?
The CAS number of Nefopam Hydrochloride is 53648-31-0.
What is the molecular formula of Nefopam Hydrochloride?
The molecular formula of Nefopam Hydrochloride is C17H20ClNO.
What is the molecular weight of Nefopam Hydrochloride?
The molecular weight of Nefopam Hydrochloride is 289.12335 g/mol.
What are the applications of Nefopam Hydrochloride?
Nefopam Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nefopam Hydrochloride (CAS...
Where can I buy Nefopam Hydrochloride?
You can request a quote for Nefopam Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nefopam Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Nefopam Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.