N-(4-Chlorophenyl)acetamide
TL;DR: N-(4-Chlorophenyl)acetamide (CAS 539-03-7) is a chemical compound with molecular formula C8H8ClNO and molecular weight 169.02943 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-chlorophenyl)acetamide
Also Known As: 4'-Chloroacetanilide, 4-Chloroacetanilide, N-(4-Chlorophenyl)acetamide, P-CHLOROACETANILIDE, N-Acetyl-p-chloroaniline
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8ClNO |
| Molecular Weight | 169.02943 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 169.02943 Da |
| Heavy Atoms | 11 |
| Complexity | 141.0 |
| Melting Point | 178-179 °C |
| Boiling Point | 333 °C |
| Density | 1.385 AT 22 °C/4 °C |
| Vapor Pressure | 0.0000963 [mmHg] |
| Solubility | PRACTICALLY INSOL IN /COLD/ WATER; READILY SOL IN ALC, ETHER; READILY SOL IN CARBON DISULFIDE; SLIGHTLY SOL IN CARBON TETRACHLORIDE, BENZENE |
| SMILES | CC(=O)NC1=CC=C(C=C1)Cl |
| InChIKey | GGUOCFNAWIODMF-UHFFFAOYSA-N |
Product Description
Applications: N-(4-Chlorophenyl)acetamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N-(4-Chlorophenyl)acetamide (CAS 539-03-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
N-(4-Chlorophenyl)acetamide (CAS 539-03-7) is a heterocyclic building block with the molecular formula C8H8ClNO and a molecular weight of 169.03 g/mol. Key physical properties include a density of 1.385 AT 22 °C/4 °C g/cm³, a solubility: PRACTICALLY INSOL IN /COLD/ WATER; READILY SOL IN ALC, ETHER; READILY SOL IN CARBON DISULFIDE; SLIGHTLY SOL IN CARBON TETRACHLORIDE, BENZENE. It is also known as 4'-Chloroacetanilide and 4-Chloroacetanilide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-(4-Chlorophenyl)acetamide
Property Insights of N-(4-Chlorophenyl)acetamide
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4-Chlorophenyl)acetamide. With a topological polar surface area (TPSA) of 29.1 Ų, N-(4-Chlorophenyl)acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-Chlorophenyl)acetamide has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(4-Chlorophenyl)acetamide?
The CAS number of N-(4-Chlorophenyl)acetamide is 539-03-7.
What is the molecular formula of N-(4-Chlorophenyl)acetamide?
The molecular formula of N-(4-Chlorophenyl)acetamide is C8H8ClNO.
What is the molecular weight of N-(4-Chlorophenyl)acetamide?
The molecular weight of N-(4-Chlorophenyl)acetamide is 169.02943 g/mol.
What are the applications of N-(4-Chlorophenyl)acetamide?
N-(4-Chlorophenyl)acetamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy N-(4-Chlorophenyl)acetamide?
You can request a quote for N-(4-Chlorophenyl)acetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(4-Chlorophenyl)acetamide?
Yes, CoreyChem provides custom synthesis services for N-(4-Chlorophenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.