Furosemide
TL;DR: Furosemide (CAS 54-31-9) is a chemical compound with molecular formula C12H11ClN2O5S and molecular weight 330.00772 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid
Also Known As: furosemide, Frusemide, Lasix, Furanthril, Furosemid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H11ClN2O5S |
| Molecular Weight | 330.00772 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 131.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 330.00772 Da |
| Heavy Atoms | 21 |
| Complexity | 481.0 |
| Melting Point | 403 °F (decomposes) (NTP, 1992) |
| Solubility | less than 1 mg/mL at 73 °F (NTP, 1992) |
| SMILES | C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl |
| InChIKey | ZZUFCTLCJUWOSV-UHFFFAOYSA-N |
Product Description
Applications: Furosemide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Furosemide is a pharmaceutical intermediate identified by CAS number 54-31-9 and the molecular formula C12H11ClN2O5S and a molecular weight of 330.01 g/mol. Physically, the compound has a solubility: less than 1 mg/mL at 73 °F (NTP, 1992). Synonyms include furosemide and Frusemide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Furosemide
Property Insights of Furosemide
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Furosemide. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Furosemide. Following Lipinski's Rule of Five, Furosemide has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Furosemide?
The CAS number of Furosemide is 54-31-9.
What is the molecular formula of Furosemide?
The molecular formula of Furosemide is C12H11ClN2O5S.
What is the molecular weight of Furosemide?
The molecular weight of Furosemide is 330.00772 g/mol.
What are the applications of Furosemide?
Furosemide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Furosemide?
You can request a quote for Furosemide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Furosemide?
Yes, CoreyChem provides custom synthesis services for Furosemide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.