Dodecamethylcyclohexasiloxane
TL;DR: Dodecamethylcyclohexasiloxane (CAS 540-97-6) is a chemical compound with molecular formula C12H36O6Si6 and molecular weight 444.11276 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Also Known As: DODECAMETHYLCYCLOHEXASILOXANE, Cyclomethicone 6, Cyclohexasiloxane, Cyclohexasiloxane, dodecamethyl-, Polysiloxane D6 CRS
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H36O6Si6 |
| Molecular Weight | 444.11276 g/mol |
| XLogP | 4.31 |
| Topological Polar Surface Area (TPSA) | 55.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 0 |
| Exact Mass | 444.11276 Da |
| Heavy Atoms | 24 |
| Complexity | 320.0 |
| Melting Point | -3 °C |
| Boiling Point | 245 °C |
| Density | 0.9672 g/cu cm at 25 °C |
| Flash Point | 91 °C (196 °F) - closed cup |
| Vapor Pressure | 0.0169 mm Hg at 25 °C |
| Refractive Index | Index of refraction = 1.4015 at 20 °C |
| Solubility | In water, 0.0051 mg/L at 23 °C |
| SMILES | C[Si]1(O[Si](O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)(C)C)C |
| InChIKey | IUMSDRXLFWAGNT-UHFFFAOYSA-N |
Product Description
Applications: Dodecamethylcyclohexasiloxane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Dodecamethylcyclohexasiloxane (CAS 540-97-6) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Dodecamethylcyclohexasiloxane (CAS 540-97-6) has the molecular formula C12H36O6Si6 and a molecular weight of 444.11 g/mol. Reported properties include a density of 0.9672 g/cu cm at 25 °C g/cm³, a solubility: In water, 0.0051 mg/L at 23 °C. It is also known as DODECAMETHYLCYCLOHEXASILOXANE and Cyclomethicone 6.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dodecamethylcyclohexasiloxane
Property Insights of Dodecamethylcyclohexasiloxane
The XLogP value of 4.31 indicates that Dodecamethylcyclohexasiloxane is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Dodecamethylcyclohexasiloxane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dodecamethylcyclohexasiloxane has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dodecamethylcyclohexasiloxane?
The CAS number of Dodecamethylcyclohexasiloxane is 540-97-6.
What is the molecular formula of Dodecamethylcyclohexasiloxane?
The molecular formula of Dodecamethylcyclohexasiloxane is C12H36O6Si6.
What is the molecular weight of Dodecamethylcyclohexasiloxane?
The molecular weight of Dodecamethylcyclohexasiloxane is 444.11276 g/mol.
What are the applications of Dodecamethylcyclohexasiloxane?
Dodecamethylcyclohexasiloxane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Dodecamethylcyclohexasiloxane (CAS 540-97-6)...
Where can I buy Dodecamethylcyclohexasiloxane?
You can request a quote for Dodecamethylcyclohexasiloxane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dodecamethylcyclohexasiloxane?
Yes, CoreyChem provides custom synthesis services for Dodecamethylcyclohexasiloxane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.