Busulfan
TL;DR: Busulfan (CAS 55-98-1) is a chemical compound with molecular formula C6H14O6S2 and molecular weight 246.02318 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-methylsulfonyloxybutyl methanesulfonate
Also Known As: busulfan, Myleran, Busulphan, Sulphabutin, Leucosulfan
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H14O6S2 |
| Molecular Weight | 246.02318 g/mol |
| XLogP | -0.5 |
| Topological Polar Surface Area (TPSA) | 104.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 246.02318 Da |
| Heavy Atoms | 14 |
| Complexity | 293.0 |
| Melting Point | 237 to 244 °F (NTP, 1992) |
| Solubility | Decomposes (NTP, 1992) |
| SMILES | CS(=O)(=O)OCCCCOS(=O)(=O)C |
| InChIKey | COVZYZSDYWQREU-UHFFFAOYSA-N |
Product Description
Applications: Busulfan is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Busulfan (CAS 55-98-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Busulfan (CAS 55-98-1) has the molecular formula C6H14O6S2 and a molecular weight of 246.02 g/mol. Reported properties include a solubility: Decomposes (NTP, 1992). It is also known as busulfan and Myleran.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Busulfan
Property Insights of Busulfan
The XLogP value of -0.5 indicates that Busulfan is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Busulfan. Following Lipinski's Rule of Five, Busulfan has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Busulfan?
The CAS number of Busulfan is 55-98-1.
What is the molecular formula of Busulfan?
The molecular formula of Busulfan is C6H14O6S2.
What is the molecular weight of Busulfan?
The molecular weight of Busulfan is 246.02318 g/mol.
What are the applications of Busulfan?
Busulfan is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Busulfan (CAS 55-98-1) with custom synthesis available from milligram...
Where can I buy Busulfan?
You can request a quote for Busulfan directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Busulfan?
Yes, CoreyChem provides custom synthesis services for Busulfan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.