Methazolamide
TL;DR: Methazolamide (CAS 554-57-4) is a chemical compound with molecular formula C5H8N4O3S2 and molecular weight 236.00378 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
Also Known As: methazolamide, Methenamide, Neptazaneat, Neptazane, Naptazane
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H8N4O3S2 |
| Molecular Weight | 236.00378 g/mol |
| XLogP | 0.1 |
| Topological Polar Surface Area (TPSA) | 139.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 236.00378 Da |
| Heavy Atoms | 14 |
| Complexity | 419.0 |
| Solubility | >35.4 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C |
| InChIKey | FLOSMHQXBMRNHR-UHFFFAOYSA-N |
Product Description
Applications: Methazolamide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Methazolamide (CAS 554-57-4) has the molecular formula C5H8N4O3S2 and a molecular weight of 236 g/mol. Reported properties include a solubility: >35.4 [ug/mL] (The mean of the results at pH 7.4). Synonyms include methazolamide and Methenamide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Methazolamide
Property Insights of Methazolamide
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methazolamide. The TPSA of 139.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Methazolamide. Following Lipinski's Rule of Five, Methazolamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Methazolamide?
The CAS number of Methazolamide is 554-57-4.
What is the molecular formula of Methazolamide?
The molecular formula of Methazolamide is C5H8N4O3S2.
What is the molecular weight of Methazolamide?
The molecular weight of Methazolamide is 236.00378 g/mol.
What are the applications of Methazolamide?
Methazolamide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Methazolamide?
You can request a quote for Methazolamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Methazolamide?
Yes, CoreyChem provides custom synthesis services for Methazolamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.