Methanesulfonyl Fluoride
TL;DR: Methanesulfonyl Fluoride (CAS 558-25-8) is a chemical compound with molecular formula CH3FO2S and molecular weight 97.98378 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methanesulfonyl fluoride
Also Known As: METHANESULFONYL FLUORIDE, Fumette, Mesyl fluoride, Fluoro methyl sulfone, fluoride
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CH3FO2S |
| Molecular Weight | 97.98378 g/mol |
| XLogP | 0.1 |
| Topological Polar Surface Area (TPSA) | 42.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 97.98378 Da |
| Heavy Atoms | 5 |
| Complexity | 95.0 |
| Boiling Point | 255 °F at 760 mmHg (EPA, 1998) |
| Density | 1.368 g/cu cm at 20 °C |
| Vapor Pressure | 10.9 [mmHg] |
| Solubility | In water, 3.00X10+4 mg/L at 20 °C |
| SMILES | CS(=O)(=O)F |
| InChIKey | KNWQLFOXPQZGPX-UHFFFAOYSA-N |
Product Description
Applications: Methanesulfonyl Fluoride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Methanesulfonyl Fluoride (CAS 558-25-8) is a pharmaceutical intermediate with the molecular formula CH3FO2S and a molecular weight of 97.98 g/mol. Key physical properties include a density of 1.368 g/cu cm at 20 °C g/cm³, a solubility: In water, 3.00X10+4 mg/L at 20 °C. Synonyms include METHANESULFONYL FLUORIDE and Fumette.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Methanesulfonyl Fluoride
Property Insights of Methanesulfonyl Fluoride
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methanesulfonyl Fluoride. With a topological polar surface area (TPSA) of 42.5 Ų, Methanesulfonyl Fluoride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methanesulfonyl Fluoride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Methanesulfonyl Fluoride?
The CAS number of Methanesulfonyl Fluoride is 558-25-8.
What is the molecular formula of Methanesulfonyl Fluoride?
The molecular formula of Methanesulfonyl Fluoride is CH3FO2S.
What is the molecular weight of Methanesulfonyl Fluoride?
The molecular weight of Methanesulfonyl Fluoride is 97.98378 g/mol.
What are the applications of Methanesulfonyl Fluoride?
Methanesulfonyl Fluoride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Methanesulfonyl Fluoride?
You can request a quote for Methanesulfonyl Fluoride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Methanesulfonyl Fluoride?
Yes, CoreyChem provides custom synthesis services for Methanesulfonyl Fluoride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.