Afloqualone
TL;DR: Afloqualone (CAS 56287-74-2) is a chemical compound with molecular formula C16H14FN3O and molecular weight 283.1121 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
Also Known As: afloqualone, Arofuto, Airomate, Aroft, Afloqualonum
Application Areas
Top 5 of 6 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H14FN3O |
| Molecular Weight | 283.1121 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 58.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 283.1121 Da |
| Heavy Atoms | 21 |
| Complexity | 439.0 |
| SMILES | CC1=CC=CC=C1N2C(=NC3=C(C2=O)C=C(C=C3)N)CF |
| InChIKey | VDOSWXIDETXFET-UHFFFAOYSA-N |
Product Description
Applications: Afloqualone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Afloqualone (CAS 56287-74-2) has the molecular formula C16H14FN3O and a molecular weight of 283.11 g/mol. Synonyms include afloqualone and Arofuto.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Afloqualone
Property Insights of Afloqualone
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Afloqualone. With a topological polar surface area (TPSA) of 58.7 Ų, Afloqualone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Afloqualone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Afloqualone?
The CAS number of Afloqualone is 56287-74-2.
What is the molecular formula of Afloqualone?
The molecular formula of Afloqualone is C16H14FN3O.
What is the molecular weight of Afloqualone?
The molecular weight of Afloqualone is 283.1121 g/mol.
What are the applications of Afloqualone?
Afloqualone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Afloqualone?
You can request a quote for Afloqualone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Afloqualone?
Yes, CoreyChem provides custom synthesis services for Afloqualone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.