Sulfamethazine
TL;DR: Sulfamethazine (CAS 57-68-1) is a chemical compound with molecular formula C12H14N4O2S and molecular weight 278.08374 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
Also Known As: sulfamethazine, Sulfadimidine, Sulfadimerazine, Sulphamethazine, Sulfamezathine
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.08374 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 106.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 278.08374 Da |
| Heavy Atoms | 19 |
| Complexity | 377.0 |
| Melting Point | 387 to 392 °F (NTP, 1992) |
| Density | 1.4655 g/cu cm |
| Solubility | less than 1 mg/mL at 68.9 °F (NTP, 1992) |
| SMILES | CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C |
| InChIKey | ASWVTGNCAZCNNR-UHFFFAOYSA-N |
Product Description
Applications: Sulfamethazine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfamethazine (CAS 57-68-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Sulfamethazine (CAS 57-68-1) is a pharmaceutical intermediate with the molecular formula C12H14N4O2S and a molecular weight of 278.08 g/mol. Key physical properties include a density of 1.4655 g/cu cm g/cm³, a solubility: less than 1 mg/mL at 68.9 °F (NTP, 1992). It is also known as sulfamethazine and Sulfadimidine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Sulfamethazine
Property Insights of Sulfamethazine
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Sulfamethazine. The TPSA of 106.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Sulfamethazine. Following Lipinski's Rule of Five, Sulfamethazine has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Sulfamethazine?
The CAS number of Sulfamethazine is 57-68-1.
What is the molecular formula of Sulfamethazine?
The molecular formula of Sulfamethazine is C12H14N4O2S.
What is the molecular weight of Sulfamethazine?
The molecular weight of Sulfamethazine is 278.08374 g/mol.
What are the applications of Sulfamethazine?
Sulfamethazine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfamethazine (CAS 57-68-1) with custom synthesis available from...
Where can I buy Sulfamethazine?
You can request a quote for Sulfamethazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sulfamethazine?
Yes, CoreyChem provides custom synthesis services for Sulfamethazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.