Brotizolam
TL;DR: Brotizolam (CAS 57801-81-7) is a chemical compound with molecular formula C15H10BrClN4S and molecular weight 391.9498 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-bromo-7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene
Also Known As: brotizolam, Lendormin, Lendorm, Mederantil, Sintonal
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H10BrClN4S |
| Molecular Weight | 391.9498 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 71.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 391.9498 Da |
| Heavy Atoms | 22 |
| Complexity | 465.0 |
| Melting Point | 211-213 |
| SMILES | CC1=NN=C2N1C3=C(C=C(S3)Br)C(=NC2)C4=CC=CC=C4Cl |
| InChIKey | UMSGKTJDUHERQW-UHFFFAOYSA-N |
Product Description
Applications: Brotizolam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Brotizolam (CAS 57801-81-7) has the molecular formula C15H10BrClN4S and a molecular weight of 391.95 g/mol. Synonyms include brotizolam and Lendormin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Brotizolam
Property Insights of Brotizolam
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Brotizolam. The TPSA of 71.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Brotizolam. Following Lipinski's Rule of Five, Brotizolam has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Brotizolam?
The CAS number of Brotizolam is 57801-81-7.
What is the molecular formula of Brotizolam?
The molecular formula of Brotizolam is C15H10BrClN4S.
What is the molecular weight of Brotizolam?
The molecular weight of Brotizolam is 391.9498 g/mol.
What are the applications of Brotizolam?
Brotizolam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Brotizolam?
You can request a quote for Brotizolam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Brotizolam?
Yes, CoreyChem provides custom synthesis services for Brotizolam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.