Domperidone
TL;DR: Domperidone (CAS 57808-66-9) is a chemical compound with molecular formula C22H24ClN5O2 and molecular weight 425.16187 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Also Known As: domperidone, Motilium, Domperidona, Domperidonum, Nauzelin
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H24ClN5O2 |
| Molecular Weight | 425.16187 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 67.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 425.16187 Da |
| Heavy Atoms | 30 |
| Complexity | 655.0 |
| Melting Point | 242.5 |
| Solubility | 0.986 |
| SMILES | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
| InChIKey | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
Product Description
Applications: Domperidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Domperidone (CAS 57808-66-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Domperidone is a pharmaceutical intermediate identified by CAS number 57808-66-9 and the molecular formula C22H24ClN5O2 and a molecular weight of 425.16 g/mol. Physically, the compound has a solubility: 0.986. It is also known as domperidone and Motilium.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Domperidone
Property Insights of Domperidone
The XLogP value of 3.9 indicates that Domperidone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Domperidone. Following Lipinski's Rule of Five, Domperidone has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Domperidone?
The CAS number of Domperidone is 57808-66-9.
What is the molecular formula of Domperidone?
The molecular formula of Domperidone is C22H24ClN5O2.
What is the molecular weight of Domperidone?
The molecular weight of Domperidone is 425.16187 g/mol.
What are the applications of Domperidone?
Domperidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Domperidone (CAS 57808-66-9) with custom...
Where can I buy Domperidone?
You can request a quote for Domperidone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Domperidone?
Yes, CoreyChem provides custom synthesis services for Domperidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.