2,3-Didemethylcolchicine
TL;DR: 2,3-Didemethylcolchicine (CAS 57866-21-4) is a chemical compound with molecular formula C20H21NO6 and molecular weight 371.1369 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,3-dihydroxy-1,10-dimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Also Known As: 2,3-Didemethylcolchicine, 2,3-Dimethylcolchicine, 2,3-didemethyl-colchicine, 2,3-Dedimethylcolchicine, N-(2,3-Dihydroxy-1,10-dimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
Technical Specifications
| Molecular Formula | C20H21NO6 |
| Molecular Weight | 371.1369 g/mol |
| XLogP | 0.2 |
| Topological Polar Surface Area (TPSA) | 105.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 371.1369 Da |
| Heavy Atoms | 27 |
| Complexity | 709.0 |
| SMILES | CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)O |
| InChIKey | DEIXKZGDCOFYAR-UHFFFAOYSA-N |
Chemical Property Profile of 2,3-Didemethylcolchicine
Property Insights of 2,3-Didemethylcolchicine
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,3-Didemethylcolchicine. The TPSA of 105.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2,3-Didemethylcolchicine. Following Lipinski's Rule of Five, 2,3-Didemethylcolchicine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2,3-Didemethylcolchicine?
The CAS number of 2,3-Didemethylcolchicine is 57866-21-4.
What is the molecular formula of 2,3-Didemethylcolchicine?
The molecular formula of 2,3-Didemethylcolchicine is C20H21NO6.
What is the molecular weight of 2,3-Didemethylcolchicine?
The molecular weight of 2,3-Didemethylcolchicine is 371.1369 g/mol.
Where can I buy 2,3-Didemethylcolchicine?
You can request a quote for 2,3-Didemethylcolchicine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2,3-Didemethylcolchicine?
Yes, CoreyChem provides custom synthesis services for 2,3-Didemethylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.