Promazine
TL;DR: Promazine (CAS 58-40-2) is a chemical compound with molecular formula C17H20N2S and molecular weight 284.1347 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine
Also Known As: promazine, Promazin, Sinophenin, Promazina, Romtiazin
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H20N2S |
| Molecular Weight | 284.1347 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 31.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 284.1347 Da |
| Heavy Atoms | 20 |
| Complexity | 285.0 |
| Melting Point | < 25 °C |
| Boiling Point | 203-210 °C at 3.00E-01 mm Hg |
| Solubility | 14.2 |
| SMILES | CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31 |
| InChIKey | ZGUGWUXLJSTTMA-UHFFFAOYSA-N |
Product Description
Applications: Promazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Promazine (CAS 58-40-2) has the molecular formula C17H20N2S and a molecular weight of 284.13 g/mol. Reported properties include a solubility: 14.2. Synonyms include promazine and Promazin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Promazine
Property Insights of Promazine
The XLogP value of 4.5 indicates that Promazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.8 Ų, Promazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Promazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Promazine?
The CAS number of Promazine is 58-40-2.
What is the molecular formula of Promazine?
The molecular formula of Promazine is C17H20N2S.
What is the molecular weight of Promazine?
The molecular weight of Promazine is 284.1347 g/mol.
What are the applications of Promazine?
Promazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Promazine?
You can request a quote for Promazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Promazine?
Yes, CoreyChem provides custom synthesis services for Promazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.