Tolazoline
TL;DR: Tolazoline (CAS 59-98-3) is a chemical compound with molecular formula C10H12N2 and molecular weight 160.10005 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-benzyl-4,5-dihydro-1H-imidazole
Also Known As: tolazoline, 2-Benzylimidazoline, Benzidazol, Benzazoline, Priscoline
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H12N2 |
| Molecular Weight | 160.10005 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 24.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 160.10005 Da |
| Heavy Atoms | 12 |
| Complexity | 169.0 |
| Melting Point | 174 |
| Solubility | 373 |
| SMILES | C1CN=C(N1)CC2=CC=CC=C2 |
| InChIKey | JIVZKJJQOZQXQB-UHFFFAOYSA-N |
Product Description
Applications: Tolazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Tolazoline (CAS 59-98-3) is a pharmaceutical intermediate with the molecular formula C10H12N2 and a molecular weight of 160.1 g/mol. Key physical properties include a solubility: 373. Synonyms include tolazoline and 2-Benzylimidazoline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tolazoline
Property Insights of Tolazoline
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tolazoline. With a topological polar surface area (TPSA) of 24.4 Ų, Tolazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tolazoline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tolazoline?
The CAS number of Tolazoline is 59-98-3.
What is the molecular formula of Tolazoline?
The molecular formula of Tolazoline is C10H12N2.
What is the molecular weight of Tolazoline?
The molecular weight of Tolazoline is 160.10005 g/mol.
What are the applications of Tolazoline?
Tolazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Tolazoline?
You can request a quote for Tolazoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tolazoline?
Yes, CoreyChem provides custom synthesis services for Tolazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.