Nerisona
TL;DR: Nerisona (CAS 59198-70-8) is a chemical compound with molecular formula C27H36F2O5 and molecular weight 478.25308 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[2-(6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] pentanoate
Also Known As: Nerisona, diflucortolone valerate, [2-(6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] pentanoate
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H36F2O5 |
| Molecular Weight | 478.25308 g/mol |
| XLogP | 4.2 |
| Topological Polar Surface Area (TPSA) | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 478.25308 Da |
| Heavy Atoms | 34 |
| Complexity | 943.0 |
| SMILES | CCCCC(=O)OCC(=O)C1C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C |
| InChIKey | HHJIUUAMYGBVSD-UHFFFAOYSA-N |
Product Description
Applications: Nerisona is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nerisona (CAS 59198-70-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nerisona (CAS 59198-70-8) is a pharmaceutical intermediate with the molecular formula C27H36F2O5 and a molecular weight of 478.25 g/mol. It is also known as Nerisona and diflucortolone valerate.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nerisona
Property Insights of Nerisona
The XLogP value of 4.2 indicates that Nerisona is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Nerisona. Following Lipinski's Rule of Five, Nerisona has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nerisona?
The CAS number of Nerisona is 59198-70-8.
What is the molecular formula of Nerisona?
The molecular formula of Nerisona is C27H36F2O5.
What is the molecular weight of Nerisona?
The molecular weight of Nerisona is 478.25308 g/mol.
What are the applications of Nerisona?
Nerisona is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nerisona (CAS 59198-70-8) with custom...
Where can I buy Nerisona?
You can request a quote for Nerisona directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nerisona?
Yes, CoreyChem provides custom synthesis services for Nerisona and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.