Sulfasalazine
TL;DR: Sulfasalazine (CAS 599-79-1) is a chemical compound with molecular formula C18H14N4O5S and molecular weight 398.06848 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-hydroxy-5-[[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl]benzoic acid
Also Known As: sulfasalazine, Azulfidine, Sulphasalazine, Salicylazosulfapyridine, Salazosulfapyridine
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H14N4O5S |
| Molecular Weight | 398.06848 g/mol |
| XLogP | -0.7 |
| Topological Polar Surface Area (TPSA) | 150.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Exact Mass | 398.06848 Da |
| Heavy Atoms | 28 |
| Complexity | 657.0 |
| SMILES | C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O |
| InChIKey | NCEXYHBECQHGNR-UHFFFAOYSA-N |
Product Description
Applications: Sulfasalazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfasalazine (CAS 599-79-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Sulfasalazine (CAS 599-79-1) is a pharmaceutical intermediate with the molecular formula C18H14N4O5S and a molecular weight of 398.07 g/mol. It is also known as sulfasalazine and Azulfidine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Sulfasalazine
Property Insights of Sulfasalazine
The XLogP value of -0.7 indicates that Sulfasalazine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 150.0 Ų indicates high polarity, suggesting Sulfasalazine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sulfasalazine has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Sulfasalazine?
The CAS number of Sulfasalazine is 599-79-1.
What is the molecular formula of Sulfasalazine?
The molecular formula of Sulfasalazine is C18H14N4O5S.
What is the molecular weight of Sulfasalazine?
The molecular weight of Sulfasalazine is 398.06848 g/mol.
What are the applications of Sulfasalazine?
Sulfasalazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfasalazine (CAS 599-79-1) with custom...
Where can I buy Sulfasalazine?
You can request a quote for Sulfasalazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sulfasalazine?
Yes, CoreyChem provides custom synthesis services for Sulfasalazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.