3-Hydroxyacetanilide
TL;DR: 3-Hydroxyacetanilide (CAS 621-42-1) is a chemical compound with molecular formula C8H9NO2 and molecular weight 151.06332 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(3-hydroxyphenyl)acetamide
Also Known As: 3-Acetamidophenol, Metacetamol, N-(3-Hydroxyphenyl)acetamide, 3'-Hydroxyacetanilide, m-Acetamidophenol
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.06332 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 151.06332 Da |
| Heavy Atoms | 11 |
| Complexity | 147.0 |
| Melting Point | 406 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
| SMILES | CC(=O)NC1=CC(=CC=C1)O |
| InChIKey | QLNWXBAGRTUKKI-UHFFFAOYSA-N |
Chemical Property Profile of 3-Hydroxyacetanilide
Property Insights of 3-Hydroxyacetanilide
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Hydroxyacetanilide. With a topological polar surface area (TPSA) of 49.3 Ų, 3-Hydroxyacetanilide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxyacetanilide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-Hydroxyacetanilide?
The CAS number of 3-Hydroxyacetanilide is 621-42-1.
What is the molecular formula of 3-Hydroxyacetanilide?
The molecular formula of 3-Hydroxyacetanilide is C8H9NO2.
What is the molecular weight of 3-Hydroxyacetanilide?
The molecular weight of 3-Hydroxyacetanilide is 151.06332 g/mol.
Where can I buy 3-Hydroxyacetanilide?
You can request a quote for 3-Hydroxyacetanilide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-Hydroxyacetanilide?
Yes, CoreyChem provides custom synthesis services for 3-Hydroxyacetanilide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.