Dihydro-5-azacytidine
TL;DR: Dihydro-5-azacytidine (CAS 62488-57-7) is a chemical compound with molecular formula C8H14N4O5 and molecular weight 246.09642 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydro-1,3,5-triazin-2-one
Also Known As: 5,6-Dihydro-5-azacytidine, Dihydro-5-azacytidine, DHAC, DHAC cpd, 5,6-dihydro-5'-azacytidine
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H14N4O5 |
| Molecular Weight | 246.09642 g/mol |
| XLogP | -3.0 |
| Topological Polar Surface Area (TPSA) | 141.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.09642 Da |
| Heavy Atoms | 17 |
| Complexity | 349.0 |
| Melting Point | 360 to 365 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) |
| SMILES | C1N=C(NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N |
| InChIKey | LJIRBXZDQGQUOO-KVTDHHQDSA-N |
Chemical Property Profile of Dihydro-5-azacytidine
Property Insights of Dihydro-5-azacytidine
The XLogP value of -3.0 indicates that Dihydro-5-azacytidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting Dihydro-5-azacytidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Dihydro-5-azacytidine has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dihydro-5-azacytidine?
The CAS number of Dihydro-5-azacytidine is 62488-57-7.
What is the molecular formula of Dihydro-5-azacytidine?
The molecular formula of Dihydro-5-azacytidine is C8H14N4O5.
What is the molecular weight of Dihydro-5-azacytidine?
The molecular weight of Dihydro-5-azacytidine is 246.09642 g/mol.
Where can I buy Dihydro-5-azacytidine?
You can request a quote for Dihydro-5-azacytidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dihydro-5-azacytidine?
Yes, CoreyChem provides custom synthesis services for Dihydro-5-azacytidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.