cefotaxime
TL;DR: cefotaxime (CAS 63527-52-6) is a chemical compound with molecular formula C16H17N5O7S2 and molecular weight 455.05695 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(acetyloxymethyl)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Also Known As: cefotaxime, Claforan, Cefotaxima, Cefotaximum, Cephotaxime
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H17N5O7S2 |
| Molecular Weight | 455.05695 g/mol |
| XLogP | -1.4 |
| Topological Polar Surface Area (TPSA) | 227.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 8 |
| Exact Mass | 455.05695 Da |
| Heavy Atoms | 30 |
| Complexity | 833.0 |
| SMILES | CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O |
| InChIKey | GPRBEKHLDVQUJE-UHFFFAOYSA-N |
Chemical Property Profile of cefotaxime
Property Insights of cefotaxime
The XLogP value of -1.4 indicates that cefotaxime is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 227.0 Ų indicates high polarity, suggesting cefotaxime may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, cefotaxime has 3 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of cefotaxime?
The CAS number of cefotaxime is 63527-52-6.
What is the molecular formula of cefotaxime?
The molecular formula of cefotaxime is C16H17N5O7S2.
What is the molecular weight of cefotaxime?
The molecular weight of cefotaxime is 455.05695 g/mol.
Where can I buy cefotaxime?
You can request a quote for cefotaxime directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for cefotaxime?
Yes, CoreyChem provides custom synthesis services for cefotaxime and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.