Clofibrate
TL;DR: Clofibrate (CAS 637-07-0) is a chemical compound with molecular formula C12H15ClO3 and molecular weight 242.07097 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
Also Known As: clofibrate, Ethyl clofibrate, Clofibrato, Atromid, Liprin
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H15ClO3 |
| Molecular Weight | 242.07097 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 35.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 242.07097 Da |
| Heavy Atoms | 16 |
| Complexity | 232.0 |
| Melting Point | 118-119 |
| Boiling Point | 149 |
| Density | 1.138-1.144 @ 20 °C |
| Refractive Index | INDEX OF REFRACTION: 1.500-1.505 @ 19.5-20.5 °C/D; MAX ABSORPTION (DEHYDRATED ETHANOL): 226 NM (A= 910, 1%, 1 CM); 280 NM (A= 87, 1%, 1 CM); 288 NM (A= 62, 1%, 1 CM) |
| Solubility | Insoluble |
| SMILES | CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl |
| InChIKey | KNHUKKLJHYUCFP-UHFFFAOYSA-N |
Product Description
Applications: Clofibrate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clofibrate (CAS 637-07-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Clofibrate (CAS 637-07-0) is a pharmaceutical intermediate with the molecular formula C12H15ClO3 and a molecular weight of 242.07 g/mol. Key physical properties include a density of 1.138-1.144 @ 20 °C g/cm³, a solubility: Insoluble. It is also known as clofibrate and Ethyl clofibrate.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clofibrate
Property Insights of Clofibrate
The XLogP value of 3.3 indicates that Clofibrate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.5 Ų, Clofibrate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clofibrate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clofibrate?
The CAS number of Clofibrate is 637-07-0.
What is the molecular formula of Clofibrate?
The molecular formula of Clofibrate is C12H15ClO3.
What is the molecular weight of Clofibrate?
The molecular weight of Clofibrate is 242.07097 g/mol.
What are the applications of Clofibrate?
Clofibrate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clofibrate (CAS 637-07-0) with custom...
Where can I buy Clofibrate?
You can request a quote for Clofibrate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clofibrate?
Yes, CoreyChem provides custom synthesis services for Clofibrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.