N-Methylcolchiceinamide
TL;DR: N-Methylcolchiceinamide (CAS 63917-71-5) is a chemical compound with molecular formula C22H26N2O5 and molecular weight 398.18417 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[1,2,3-trimethoxy-10-(methylamino)-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Methylcolchaminone, N-Methylcolchiceinamide, Methylaminocolchicide, Colchicoinamide, N-Methyl-, 10-Demethoxy-10-methylaminocolchicine
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H26N2O5 |
| Molecular Weight | 398.18417 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 85.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 398.18417 Da |
| Heavy Atoms | 29 |
| Complexity | 741.0 |
| SMILES | CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)NC)OC)OC)OC |
| InChIKey | NLBLGIGBTKMQSA-UHFFFAOYSA-N |
Chemical Property Profile of N-Methylcolchiceinamide
Property Insights of N-Methylcolchiceinamide
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Methylcolchiceinamide. The TPSA of 85.9 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Methylcolchiceinamide. Following Lipinski's Rule of Five, N-Methylcolchiceinamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-Methylcolchiceinamide?
The CAS number of N-Methylcolchiceinamide is 63917-71-5.
What is the molecular formula of N-Methylcolchiceinamide?
The molecular formula of N-Methylcolchiceinamide is C22H26N2O5.
What is the molecular weight of N-Methylcolchiceinamide?
The molecular weight of N-Methylcolchiceinamide is 398.18417 g/mol.
Where can I buy N-Methylcolchiceinamide?
You can request a quote for N-Methylcolchiceinamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-Methylcolchiceinamide?
Yes, CoreyChem provides custom synthesis services for N-Methylcolchiceinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.