Metformin
TL;DR: Metformin (CAS 657-24-9) is a chemical compound with molecular formula C4H11N5 and molecular weight 129.10144 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(diaminomethylidene)-1,1-dimethylguanidine
Also Known As: metformin, 1,1-Dimethylbiguanide, Metiguanide, Metformine, Dimethylbiguanide
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H11N5 |
| Molecular Weight | 129.10144 g/mol |
| XLogP | -1.3 |
| Topological Polar Surface Area (TPSA) | 91.5 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 129.10144 Da |
| Heavy Atoms | 9 |
| Complexity | 132.0 |
| Melting Point | 223-226 °C |
| Boiling Point | 224.1ºC at 760 mmHg |
| Solubility | Freely soluble |
| SMILES | CN(C)C(=N)N=C(N)N |
| InChIKey | XZWYZXLIPXDOLR-UHFFFAOYSA-N |
Product Description
Applications: Metformin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Metformin (CAS 657-24-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Metformin (CAS 657-24-9) is a pharmaceutical intermediate with the molecular formula C4H11N5 and a molecular weight of 129.1 g/mol. Key physical properties include a solubility: Freely soluble. It is also known as metformin and 1,1-Dimethylbiguanide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Metformin
Property Insights of Metformin
The XLogP value of -1.3 indicates that Metformin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 91.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Metformin. Following Lipinski's Rule of Five, Metformin has 3 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Metformin?
The CAS number of Metformin is 657-24-9.
What is the molecular formula of Metformin?
The molecular formula of Metformin is C4H11N5.
What is the molecular weight of Metformin?
The molecular weight of Metformin is 129.10144 g/mol.
What are the applications of Metformin?
Metformin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Metformin (CAS 657-24-9) with custom...
Where can I buy Metformin?
You can request a quote for Metformin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Metformin?
Yes, CoreyChem provides custom synthesis services for Metformin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.