Methyl Methanesulfonate
TL;DR: Methyl Methanesulfonate (CAS 66-27-3) is a chemical compound with molecular formula C2H6O3S and molecular weight 110.00377 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl methanesulfonate
Also Known As: METHYL METHANESULFONATE, Methyl mesylate, Methylmethanesulfonate, as-Dimethyl sulfite, Methanesulfonic acid methyl ester
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C2H6O3S |
| Molecular Weight | 110.00377 g/mol |
| XLogP | -0.4 |
| Topological Polar Surface Area (TPSA) | 51.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 110.00377 Da |
| Heavy Atoms | 6 |
| Complexity | 105.0 |
| Melting Point | 68 °F (NTP, 1992) |
| Boiling Point | 396 to 397 °F at 760 mmHg (NTP, 1992) |
| Density | 1.2943 at 68 °F (NTP, 1992) - Denser than water; will sink |
| Flash Point | 220 °F (NTP, 1992) |
| Vapor Pressure | 0.31 [mmHg] |
| Refractive Index | Index of refraction 1.4140 at 20 °C/D |
| Solubility | greater than or equal to 100 mg/mL at 73 °F (NTP, 1992) |
| SMILES | COS(=O)(=O)C |
| InChIKey | MBABOKRGFJTBAE-UHFFFAOYSA-N |
Product Description
Applications: Methyl Methanesulfonate is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Methyl Methanesulfonate is a heterocyclic building block identified by CAS number 66-27-3 and the molecular formula C2H6O3S and a molecular weight of 110 g/mol. Physically, the compound has a density of 1.2943 at 68 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: greater than or equal to 100 mg/mL at 73 °F (NTP, 1992). Synonyms include METHYL METHANESULFONATE and Methyl mesylate.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Methyl Methanesulfonate
Property Insights of Methyl Methanesulfonate
The XLogP value of -0.4 indicates that Methyl Methanesulfonate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 51.8 Ų, Methyl Methanesulfonate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methyl Methanesulfonate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Methyl Methanesulfonate?
The CAS number of Methyl Methanesulfonate is 66-27-3.
What is the molecular formula of Methyl Methanesulfonate?
The molecular formula of Methyl Methanesulfonate is C2H6O3S.
What is the molecular weight of Methyl Methanesulfonate?
The molecular weight of Methyl Methanesulfonate is 110.00377 g/mol.
What are the applications of Methyl Methanesulfonate?
Methyl Methanesulfonate is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Methyl Methanesulfonate?
You can request a quote for Methyl Methanesulfonate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Methyl Methanesulfonate?
Yes, CoreyChem provides custom synthesis services for Methyl Methanesulfonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.