Apraclonidine
TL;DR: Apraclonidine (CAS 66711-21-5) is a chemical compound with molecular formula C9H10Cl2N4 and molecular weight 244.02826 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
Also Known As: apraclonidine, Aplonidine, Apraclonidina, Iopidine, 4-Aminoclonidine
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H10Cl2N4 |
| Molecular Weight | 244.02826 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 62.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.02826 Da |
| Heavy Atoms | 15 |
| Complexity | 246.0 |
| Solubility | 4.09e-01 g/L |
| SMILES | C1CN=C(N1)NC2=C(C=C(C=C2Cl)N)Cl |
| InChIKey | IEJXVRYNEISIKR-UHFFFAOYSA-N |
Product Description
Applications: Apraclonidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Apraclonidine (CAS 66711-21-5) has the molecular formula C9H10Cl2N4 and a molecular weight of 244.03 g/mol. Reported properties include a solubility: 4.09e-01 g/L. Synonyms include apraclonidine and Aplonidine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Apraclonidine
Property Insights of Apraclonidine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Apraclonidine. The TPSA of 62.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Apraclonidine. Following Lipinski's Rule of Five, Apraclonidine has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Apraclonidine?
The CAS number of Apraclonidine is 66711-21-5.
What is the molecular formula of Apraclonidine?
The molecular formula of Apraclonidine is C9H10Cl2N4.
What is the molecular weight of Apraclonidine?
The molecular weight of Apraclonidine is 244.02826 g/mol.
What are the applications of Apraclonidine?
Apraclonidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Apraclonidine?
You can request a quote for Apraclonidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Apraclonidine?
Yes, CoreyChem provides custom synthesis services for Apraclonidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.