Arotinolol
TL;DR: Arotinolol (CAS 68377-92-4) is a chemical compound with molecular formula C15H21N3O2S3 and molecular weight 371.0796 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-[2-[3-(tert-butylamino)-2-hydroxypropyl]sulfanyl-1,3-thiazol-4-yl]thiophene-2-carboxamide
Also Known As: Arotinolol, Arotinololum, Arotinolol [INN], Arotinolo, Arotinololum [Latin]
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H21N3O2S3 |
| Molecular Weight | 371.0796 g/mol |
| XLogP | 2.3 |
| Topological Polar Surface Area (TPSA) | 170.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 371.0796 Da |
| Heavy Atoms | 23 |
| Complexity | 406.0 |
| Melting Point | 149-153ºC |
| Boiling Point | 599ºC at 760 mmHg |
| Solubility | Slightly soluble |
| SMILES | CC(C)(C)NCC(CSC1=NC(=CS1)C2=CC=C(S2)C(=O)N)O |
| InChIKey | BHIAIPWSVYSKJS-UHFFFAOYSA-N |
Product Description
Applications: Arotinolol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Arotinolol (CAS 68377-92-4) has the molecular formula C15H21N3O2S3 and a molecular weight of 371.08 g/mol. Reported properties include a solubility: Slightly soluble. Synonyms include Arotinolol and Arotinololum.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Arotinolol
Property Insights of Arotinolol
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Arotinolol. The TPSA of 170.0 Ų indicates high polarity, suggesting Arotinolol may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Arotinolol has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Arotinolol?
The CAS number of Arotinolol is 68377-92-4.
What is the molecular formula of Arotinolol?
The molecular formula of Arotinolol is C15H21N3O2S3.
What is the molecular weight of Arotinolol?
The molecular weight of Arotinolol is 371.0796 g/mol.
What are the applications of Arotinolol?
Arotinolol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Arotinolol?
You can request a quote for Arotinolol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Arotinolol?
Yes, CoreyChem provides custom synthesis services for Arotinolol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.