Liothyronine
TL;DR: Liothyronine (CAS 6893-02-3) is a chemical compound with molecular formula C15H12I3NO4 and molecular weight 650.7901 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Also Known As: liothyronine, triiodothyronine, 3,3',5-Triiodo-L-thyronine, Liothyronin, Tresitope
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H12I3NO4 |
| Molecular Weight | 650.7901 g/mol |
| XLogP | 1.7 |
| Topological Polar Surface Area (TPSA) | 92.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 650.7901 Da |
| Heavy Atoms | 23 |
| Complexity | 402.0 |
| Melting Point | 230 |
| Boiling Point | 563 |
| Solubility | Very slightly soluble |
| SMILES | C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O |
| InChIKey | AUYYCJSJGJYCDS-LBPRGKRZSA-N |
Product Description
Applications: Liothyronine is used in pharmaceutical synthesis routes and API production, as well as analytical chemistry as a reagent, standard, or reference material. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Liothyronine (CAS 6893-02-3) has the molecular formula C15H12I3NO4 and a molecular weight of 650.79 g/mol. Reported properties include a solubility: Very slightly soluble. Synonyms include liothyronine and triiodothyronine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Liothyronine
Property Insights of Liothyronine
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Liothyronine. The TPSA of 92.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Liothyronine. Following Lipinski's Rule of Five, Liothyronine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Liothyronine?
The CAS number of Liothyronine is 6893-02-3.
What is the molecular formula of Liothyronine?
The molecular formula of Liothyronine is C15H12I3NO4.
What is the molecular weight of Liothyronine?
The molecular weight of Liothyronine is 650.7901 g/mol.
What are the applications of Liothyronine?
Liothyronine is used in pharmaceutical synthesis routes and API production, as well as analytical chemistry as a reagent, standard, or reference material. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Liothyronine?
You can request a quote for Liothyronine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Liothyronine?
Yes, CoreyChem provides custom synthesis services for Liothyronine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.