Pyroglutamyl-histidyl-glycine
TL;DR: Pyroglutamyl-histidyl-glycine (CAS 69275-10-1) is a chemical compound with molecular formula C13H17N5O5 and molecular weight 323.12296 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[[(2S)-3-(4H-imidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]acetic acid
Also Known As: Pglu-his-gly, Pyr-his-gly, Pglu-his-gly-OH, pyroglutamyl-histidyl-glycine, Anorexigenic peptide
Technical Specifications
| Molecular Formula | C13H17N5O5 |
| Molecular Weight | 323.12296 g/mol |
| XLogP | -2.4 |
| Topological Polar Surface Area (TPSA) | 149.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 323.12296 Da |
| Heavy Atoms | 23 |
| Complexity | 573.0 |
| SMILES | C1CC(=O)N[C@@H]1C(=O)N[C@@H](CC2C=NC=N2)C(=O)NCC(=O)O |
| InChIKey | VTKWFWXOVZIATL-NPPUSCPJSA-N |
Chemical Property Profile of Pyroglutamyl-histidyl-glycine
Property Insights of Pyroglutamyl-histidyl-glycine
The XLogP value of -2.4 indicates that Pyroglutamyl-histidyl-glycine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 149.0 Ų indicates high polarity, suggesting Pyroglutamyl-histidyl-glycine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-histidyl-glycine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-histidyl-glycine?
The CAS number of Pyroglutamyl-histidyl-glycine is 69275-10-1.
What is the molecular formula of Pyroglutamyl-histidyl-glycine?
The molecular formula of Pyroglutamyl-histidyl-glycine is C13H17N5O5.
What is the molecular weight of Pyroglutamyl-histidyl-glycine?
The molecular weight of Pyroglutamyl-histidyl-glycine is 323.12296 g/mol.
Where can I buy Pyroglutamyl-histidyl-glycine?
You can request a quote for Pyroglutamyl-histidyl-glycine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Pyroglutamyl-histidyl-glycine?
Yes, CoreyChem provides custom synthesis services for Pyroglutamyl-histidyl-glycine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.