Trifluridine
TL;DR: Trifluridine (CAS 70-00-8) is a chemical compound with molecular formula C10H11F3N2O5 and molecular weight 296.062 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
Also Known As: Trifluridine, TRIFLUOROTHYMIDINE, Viroptic, 5-Trifluorothymidine, Trifluridina
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H11F3N2O5 |
| Molecular Weight | 296.062 g/mol |
| XLogP | -0.5 |
| Topological Polar Surface Area (TPSA) | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 296.062 Da |
| Heavy Atoms | 20 |
| Complexity | 464.0 |
| Melting Point | 186-189 |
| Solubility | Soluble |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O |
| InChIKey | VSQQQLOSPVPRAZ-RRKCRQDMSA-N |
Product Description
Applications: Trifluridine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trifluridine (CAS 70-00-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Trifluridine is a pharmaceutical intermediate identified by CAS number 70-00-8 and the molecular formula C10H11F3N2O5 and a molecular weight of 296.06 g/mol. Physically, the compound has a solubility: Soluble. It is also known as Trifluridine and TRIFLUOROTHYMIDINE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trifluridine
Property Insights of Trifluridine
The XLogP value of -0.5 indicates that Trifluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Trifluridine. Following Lipinski's Rule of Five, Trifluridine has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trifluridine?
The CAS number of Trifluridine is 70-00-8.
What is the molecular formula of Trifluridine?
The molecular formula of Trifluridine is C10H11F3N2O5.
What is the molecular weight of Trifluridine?
The molecular weight of Trifluridine is 296.062 g/mol.
What are the applications of Trifluridine?
Trifluridine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trifluridine (CAS 70-00-8) with custom...
Where can I buy Trifluridine?
You can request a quote for Trifluridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trifluridine?
Yes, CoreyChem provides custom synthesis services for Trifluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.