Eflornithine
TL;DR: Eflornithine (CAS 70052-12-9) is a chemical compound with molecular formula C6H12F2N2O2 and molecular weight 182.08669 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,5-diamino-2-(difluoromethyl)pentanoic acid
Also Known As: EFLORNITHINE, dfmo, Difluoromethylornithine, Ornidyl, Eflornitina
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H12F2N2O2 |
| Molecular Weight | 182.08669 g/mol |
| XLogP | -2.9 |
| Topological Polar Surface Area (TPSA) | 89.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 182.08669 Da |
| Heavy Atoms | 12 |
| Complexity | 166.0 |
| Boiling Point | 347 |
| Solubility | >10 mg/mL |
| SMILES | C(CC(C(F)F)(C(=O)O)N)CN |
| InChIKey | VLCYCQAOQCDTCN-UHFFFAOYSA-N |
Product Description
Applications: Eflornithine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Eflornithine (CAS 70052-12-9) is a pharmaceutical intermediate with the molecular formula C6H12F2N2O2 and a molecular weight of 182.09 g/mol. Key physical properties include a solubility: >10 mg/mL. Synonyms include EFLORNITHINE and dfmo.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Eflornithine
Property Insights of Eflornithine
The XLogP value of -2.9 indicates that Eflornithine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 89.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Eflornithine. Following Lipinski's Rule of Five, Eflornithine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Eflornithine?
The CAS number of Eflornithine is 70052-12-9.
What is the molecular formula of Eflornithine?
The molecular formula of Eflornithine is C6H12F2N2O2.
What is the molecular weight of Eflornithine?
The molecular weight of Eflornithine is 182.08669 g/mol.
What are the applications of Eflornithine?
Eflornithine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Eflornithine?
You can request a quote for Eflornithine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Eflornithine?
Yes, CoreyChem provides custom synthesis services for Eflornithine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.