Nafimidone monohydrochloride
TL;DR: Nafimidone monohydrochloride (CAS 70891-37-1) is a chemical compound with molecular formula C15H13ClN2O and molecular weight 272.07166 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-imidazol-1-yl-1-naphthalen-2-ylethanone;hydrochloride
Also Known As: Nafimidone hydrochloride, Nafimidone HCl, nafimidone monohydrochloride, Nafimidone hydrochloride [USAN], Nafimidone hydrochloride (USAN)
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H13ClN2O |
| Molecular Weight | 272.07166 g/mol |
| XLogP | 3.34 |
| Topological Polar Surface Area (TPSA) | 34.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.07166 Da |
| Heavy Atoms | 19 |
| Complexity | 305.0 |
| SMILES | C1=CC=C2C=C(C=CC2=C1)C(=O)CN3C=CN=C3.Cl |
| InChIKey | DOBNXXMVNHWJKU-UHFFFAOYSA-N |
Chemical Property Profile of Nafimidone monohydrochloride
Property Insights of Nafimidone monohydrochloride
The XLogP value of 3.34 indicates that Nafimidone monohydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.9 Ų, Nafimidone monohydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nafimidone monohydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nafimidone monohydrochloride?
The CAS number of Nafimidone monohydrochloride is 70891-37-1.
What is the molecular formula of Nafimidone monohydrochloride?
The molecular formula of Nafimidone monohydrochloride is C15H13ClN2O.
What is the molecular weight of Nafimidone monohydrochloride?
The molecular weight of Nafimidone monohydrochloride is 272.07166 g/mol.
Where can I buy Nafimidone monohydrochloride?
You can request a quote for Nafimidone monohydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nafimidone monohydrochloride?
Yes, CoreyChem provides custom synthesis services for Nafimidone monohydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.